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Establish an ion chromatography-conductivity detection method for simultaneous determination of 13 anions in drinking water. Method: The Metrosep A Supp 5-250 anion analysis column was used in combination with the Metrosep A Supp 1 Guard guard column. The eluent was 3.2 mmol / L Na2CO3-1.0 mmol / L NaHCO3, the flow rate was 0.7 ml / min, and the injection volume was 100 μl. Results: Within a certain concentration range, each test object had a good linear relationship (r> 0.999), and the detection limit was low (0.0003 mg / L ～ 0.0134 mg / L). Standard recovery, the recovery rate is between 93% and 104%. Conclusion: This method is simple, sensitive and accurate. It can separate and measure 13 anions in drinking water at the same time with one sample injection, which can meet the requirements of water quality testing in China's "Sanitary Standards for Drinking Water".