Last fall, personal gene company 23andme launched a new genetic testing product, which is based on the Food and Drug Administration (FDA) regulations for individual genetic testing products. A compromise was made. The information that new products can analyze is still very diverse: from the extent to which you inherit the ancestral genes, to how much you prefer to consume caffeine. At the same time, the test will let you know if the genes in your body have mutated and what diseases are associated with them. Business Insider reporter Lydia Ramsey started the first time the product was released and wrote an experience report. If you are eager to test domestic genetic products, you may wish to read this report on the originator of personal genetic testing products 23andMe, and then decide not too late~ I was interested in 23andMe's plan to develop targeted drugs based on genetic information. But I am also curious as to how many chances I may have with a child, or whether the family's health problems can be found in a saliva. Here is my experience: A few days after booking the product, my 23andMe is coming soon! The color is so colorful that I can't wait to open it. Detect the instructions, a tube that spits me, and a special bag to collect the finished tube. 23andMe's full suite of genetic testing components Saliva is one of the many ways to collect DNA, which is less offensive. In fact, spitting into the tube is not as easy as I thought, so my colleague endured that I spent five minutes doing the activity. The reason why 23andMe needs so much saliva is that once the first test or analysis process fails, there is enough saliva to come back for the second time. Finally, finally, my saliva reached the standard line. Next, seal the tube into the bag and send it away. Before sending the courier, I have to register my test online. At the same time, I have to decide whether I am willing to use genetic information for disease treatment research. In the spirit of dedication to science, I agree and sign with 80% of 23andMe users. This set of testing tools sent back the postage. I just need to send it to the nearest mailbox and send it on the road! The box is very intimately labeled "licensed human specimens", indicating that the package does not contain any substances that may be transmitted. After seven weeks, the results were received in the mailbox. In total, 62 reports were published based on 23 pairs of chromosomes, including family history to body traits, and the disease genes that may be passed on to children. Of course, I will start from the analysis of the ancestral source. Unsurprisingly, I am a Nordic. This comes from the 30 reference people, or the generations of people living in a certain geographical area, or the grandparents are derived from the genetic information of other 23andMe users in the same place. My DNA is the point of comparison with these people. The new test can also tell me more about health and fitness. I found that I am not easy to have the kind of "sprint / strength muscles" because of the lack of two muscle proteins that are specifically associated with Olympic sprinters. However, this result cannot be used as a diagnosis to understand. If I am really a good sprinter, this can only be a good support for me. Missing two kinds of proteins, it seems to say goodbye to the strength muscles. Two years ago, 23andMe was in trouble: the FDA thought that their tests might be interpreted as medical advice. So, I am not surprised to see that the "limitations" of these tests are so clearly stated. It now appears that the new test meets the standards of the Clinical Laboratory Improvement Act and the FDA. Limitations: All variables related to muscle composition are not detected, and other factors such as lifestyle effects are not excluded. As a latte fanatic, I was shocked when I saw that I was considered to consume less caffeine than the average person. However, 23andMe explained that this result only means that I have a tendency to consume less caffeine. Environmental factors like the rhythmic news industry will also change the way coffee is consumed. Gene expression altered by the external environment: caffeine intake Incredibly, a small sample of saliva can detect this difference. Research techniques based on DNA samples have continued to improve in recent years, but still have many limitations. However, when it began to analyze my physical characteristics, many analyses were surprisingly impressive. ... For example, I have a 96% chance of not even my eyebrows (the left and right eyebrows are connected together), this is true, my eyebrows really don't last long. Other sexual characteristics of the test, including eye color and hair quality, are related to specific areas of the gene, many of which have only recently been discovered. Regarding the eyebrow shape, 23andMe is right! But there are also many conclusions that are unexpected. For example, 99% of me will not grow red hair. In fact, my sister and a cousin are red hair. I was born with a reddish blond hair, so I thought that red hair is a family character. However, Caremela Thompson, genetic consultant for Genetic Discovery SF, told me that these results have been heard. "Thinking about the complexity of the hair color gene, I will never arbitrarily say that it means your child will not grow red hair." . Hair color, 23andMe made a mistake. The most controversial part is at the end: genetic disease testing, which indicates that I may carry a specific disease-causing gene that may be passed on to the child and cause that genetic disease. This piece is the part that requires FDA approval, so 23andMe is extremely cautious in this statement, repeatedly stressing that this cannot be used as a clinical reference for his own health. Unlike the previous generation 23andMe test products, you will not see the risk of breast cancer with the BRCA gene, nor the possibility of Alzheimer's disease. If I really carry some very rare disease-causing gene, but still want to have a baby, Thompson consultants suggest to talk to a genetic consultant before talking. At that time, it would be better to have a genetic diagnosis test with a doctor. Inspiration: A test of 199 US dollars, although a little beyond my budget for a holiday gift, but I will still encourage friends and family may wish to try. Even if there is nothing to refer to, it is not a bad thing to contribute to research and keep scientific information updated. In addition, it is extremely interesting to see how much your DNA is similar to the ancient race. This article was translated from Business Insider, the original title is "I tried 23 and Me's new genetics test — and now I know why the company caused such a stir", (http://), please be sure to indicate this article and the original link. (Editor) 
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